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Cyproheptadine

An antihistamine for allergies, itching and hives.

Clinical information

Common uses

  • allergic rhinitis and conjunctivitis
  • hives and swelling (urticaria, angioedema)
  • cold urticaria and dermatographism
  • add-on for allergic reactions after emergency treatment

Common side effects

  • sedation and sleepiness
  • dizziness
  • dry mouth
  • increased appetite and weight gain

Cautions

  • not for newborns or breastfeeding mothers
  • avoid with glaucoma, stomach ulcer or prostate problems
  • may reduce alertness — care when driving
  • overdose in children can be dangerous

Interactions

  • MAO inhibitors (contraindicated)
  • alcohol and other sedatives (added drowsiness)

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, cyproheptadine hydrochloride solution label, setid 582b86c6-f9b2-278d-e063-6394a90a923d (accessed 2026-08-16)

Approved brands & formulations5

Brand nameDosage formStrengthImporterCategory
CiplactinTablet4 mgauthorized medicine importersPOM
CiplactinOral Liquid2 mg/5mlauthorized medicine importersPOM
CyproTablet4 mgauthorized medicine importersPOM
CyproheptadineTablet4 mg—POM
CyproheptadineOral Liquid2 mg/5ml—POM
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