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Colistimethate Sodium

An injected antibiotic for serious infections by certain gram-negative bacteria.

Clinical information

Common uses

  • serious gram-negative infections, especially Pseudomonas aeruginosa

Common side effects

  • stomach upset
  • tingling of hands, feet or tongue
  • dizziness or vertigo
  • slurred speech
  • itching or rash

Cautions

  • can harm the kidneys — dose-related, reversible on stopping
  • nerve symptoms — do not drive or use machinery
  • do not exceed the maximum daily dose

Interactions

  • aminoglycoside and polymyxin antibiotics (nerve-muscle effects)
  • surgical muscle relaxants (e.g. tubocurarine, succinylcholine)
  • sodium cephalothin (kidney damage risk — avoid)

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, colistimethate for injection label, setid 8ec7dc90-825c-422e-9f4b-c8ace9d93af5 (accessed 2026-08-16)

Approved brands & formulations2

Brand nameDosage formStrengthImporterCategory
Colistimethate SodiumParenteral ( Injection )1 IUMFDA designated importers with Pre Authorization approval before importhospital
Colistimethate SodiumParenteral ( Injection )50 mgMFDA designated importers with Pre Authorization approval before importhospital
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