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Medicinecontrolled

Codeine

An opioid painkiller for pain, and sometimes cough or diarrhoea.

Clinical information

Common uses

  • pain after an operation or injury
  • dry or painful cough
  • diarrhoea

Common side effects

  • constipation
  • feeling or being sick
  • feeling sleepy or tired
  • sweating

Cautions

  • can be addictive — do not stop suddenly after long use
  • taking an extra dose can be dangerous
  • may not suit asthma, lung problems or head injury
  • not for children under 12

Interactions

  • other opioid painkillers such as co-codamol
  • medicines for depression or mental health conditions
  • sedating antihistamines
  • anti-sickness medicines
  • other diarrhoea medicines
  • alcohol and recreational drugs (serious side effects)

Pregnancy: sometimes used if needed — discuss risks with your doctor

Reference information, not medical advice — always follow your doctor or pharmacist. Source: NHS Medicines A–Z, nhs.uk/medicines/codeine (accessed 2026-08-16)

Approved brands & formulations3

Brand nameDosage formStrengthImporterCategory
CodeineTablet20 mgMFDA designated importers with Pre Authorization approval before importcontrolled
CodeineTablet30 mgMFDA designated importers with Pre Authorization approval before importcontrolled
CodeineOral Liquid5 mg/mlPOM
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