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Chlorambucil

A chemotherapy tablet for chronic lymphocytic leukaemia and lymphomas.

Clinical information

Common uses

  • chronic lymphocytic leukaemia
  • malignant lymphomas including Hodgkin's disease

Cautions

  • severely suppresses bone marrow (boxed warning)
  • carcinogenic — can itself cause leukaemia (boxed warning)
  • causes infertility, which may be permanent (boxed warning)
  • stop promptly if a skin rash develops

Interactions

  • none known (per label)

Pregnancy: avoid — can harm an unborn baby

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, LEUKERAN (chlorambucil) tablet label, setid 58a3c995-5ad6-465d-8437-5970c9088213 (accessed 2026-08-16)

Approved brands & formulations1

Brand nameDosage formStrengthImporterCategory
ChlorambucilTablet2mgMFDA designated importers with Pre Authorization approval before importhospital
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