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MedicinePOM

Ceritinib

A targeted cancer tablet (ALK kinase inhibitor) for a type of lung cancer.

Clinical information

Common uses

  • ALK-positive metastatic non-small cell lung cancer

Common side effects

  • diarrhoea
  • nausea and vomiting
  • stomach pain
  • tiredness

Cautions

  • can damage the liver — monthly liver blood tests
  • lung inflammation (pneumonitis) means stopping permanently
  • heart rhythm changes, slow heart rate, high blood sugar possible
  • can harm an unborn baby — use effective contraception

Interactions

  • strong CYP3A inhibitors or inducers — avoid
  • sensitive CYP3A substrate medicines — avoid
  • some CYP2C9 substrate medicines — avoid

Pregnancy: avoid — can harm an unborn baby

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, ZYKADIA (ceritinib) tablet label, setid fff5d805-4ffd-4e8e-8e63-6f129697563e (accessed 2026-08-16)

Approved brands & formulations1

Brand nameDosage formStrengthImporterCategory
CeritinibCapsule150mgPOM
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