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Cefotaxime

An injectable cephalosporin antibiotic for serious bacterial infections.

Clinical information

Common uses

  • bacterial infections (cephalosporin antibiotic given by injection)

Cautions

  • not for people allergic to cephalosporin antibiotics
  • caution with penicillin allergy
  • rapid injection into a central line has caused dangerous heart rhythms
  • diarrhoea can signal C. difficile infection

Interactions

  • probenecid (raises cefotaxime levels — avoid high doses together)
  • aminoglycosides, NSAIDs and furosemide (added kidney strain)

Pregnancy: no harm in animal studies — use only if clearly needed

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, cefotaxime injection label, setid ed23b6bc-32c7-4c50-a53d-313ae78e5623 (accessed 2026-08-16)

Approved brands & formulations11

Brand nameDosage formStrengthImporterCategory
CefotaximeParenteral ( Injection )250mgPOM
CefotaximeParenteral ( Injection )1 gPOM
CefotaximeParenteral ( Injection )500mgPOM
KalfoximParenteral ( Injection )1g/ vial ( 4ml )State Trading Organization PlcPOM
OMNICEFParenteral ( Injection- dry powder)1 gADK Pharmaceutical Company Pvt. LtdPOM
OMNICEFParenteral ( Injection- dry powder)500mgADK Pharmaceutical Company Pvt. LtdPOM
Oritaxim 1000Parenteral ( Injection- dry powder)1000mg/vialauthorized importers after registration of the productPOM
ZetaximParenteral ( Injection )500mgauthorized medicine importersPOM
ZetaximParenteral ( Injection )500mgauthorized medicine importersPOM
ZetaximParenteral ( Injection )1 g IPauthorized medicine importersPOM
ZetaximParenteral ( Injection )1 gauthorized medicine importersPOM
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