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Bendamustine

An intravenous chemotherapy (alkylating drug) for certain blood cancers.

Clinical information

Common uses

  • chronic lymphocytic leukaemia
  • indolent B-cell non-Hodgkin lymphoma after rituximab

Common side effects

  • low blood counts (anaemia, low platelets, low white cells)
  • feeling sick
  • vomiting
  • fever
  • tiredness

Cautions

  • lowers blood counts — infection risk, counts monitored
  • severe allergic and infusion reactions can occur
  • tumour lysis syndrome can cause kidney failure
  • severe skin reactions — stop if they develop

Interactions

  • CYP1A2 inducers or inhibitors (consider alternatives)

Pregnancy: can harm an unborn baby — use effective contraception

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, bendamustine hydrochloride label, setid f359e7c6-d104-457d-a7fe-597c74440353 (accessed 2026-08-16)

Approved brands & formulations1

Brand nameDosage formStrengthImporterCategory
BendamustineParenteral ( Infusion- Powder for concentrate for solution )2.5mg/ml (100mg/40ml)MFDA designated importers with Pre Authorization approval before importhospital
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