Clinical information
Common uses
- HIV-1 infection, as a ritonavir-boosted regimen with other antiretrovirals
Common side effects
- feeling sick
- yellowing of the skin or eyes (jaundice)
- rash
- headache
- stomach pain
Cautions
- ritonavir boosting strengthens many drug interactions — check every new medicine
- can slow the heart's electrical conduction
- stop if a severe rash develops
- not recommended with any degree of liver impairment
Interactions
- amiodarone or quinidine (do not combine — heart rhythm risk)
- rifampicin, carbamazepine, phenytoin, St John's wort (do not combine)
- simvastatin and lovastatin (do not combine)
- rivaroxaban and similar blood thinners (bleeding risk)
- high-dose ketoconazole or itraconazole (use cautiously)
- voriconazole (generally avoid)
Pregnancy: no increased risk of birth defects seen; boosted regimen required in pregnancy
Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, atazanavir sulfate label, setid 7fbea274-d6b5-4faa-bbf0-05fefab42114 (accessed 2026-08-16)