MedicinePOM

Apalutamide

An androgen receptor inhibitor tablet used to treat prostate cancer.

Clinical information

Common uses

metastatic castration-sensitive prostate cancer
non-metastatic castration-resistant prostate cancer

Common side effects

tiredness
joint pain
rash
decreased appetite
diarrhoea

Cautions

heart and stroke events have occurred — heart risk is monitored
increases fractures and falls
seizures can occur — stopped permanently if one happens
rare severe skin reactions — report rash, fever or mouth sores

Interactions

can make many other medicines less effective (CYP3A4 and similar substrates)
can falsely raise digoxin blood-test results

Pregnancy: can harm an unborn baby — not for use in women

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, ERLEADA (apalutamide) label, setid d1cda4f7-cb33-46ea-b9ac-431f6452b1a5 (accessed 2026-08-16)

Approved brands & formulations2

Brand name	Dosage form	Strength	Importer	Category
Apalutamide	Tablet	60mg	—	POM
lorlatinib	Tablet	100mg	—	POM