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Amikacin

An aminoglycoside antibiotic given by injection for serious bacterial infections.

Clinical information

Common uses

  • short-term treatment of serious infections
  • Gram-negative bacteria such as Pseudomonas, E. coli and Klebsiella

Common side effects

  • hearing loss or ringing in the ears
  • dizziness or spinning sensation (vertigo)
  • kidney problems
  • numbness, skin tingling or muscle twitching

Cautions

  • can cause permanent hearing and balance damage (boxed warning)
  • can damage the kidneys — kidney function is monitored (boxed warning)
  • muscle weakness and breathing problems can occur after injection
  • not usually given for more than 14 days

Interactions

  • other kidney- or ear-toxic medicines (vancomycin, amphotericin B, cisplatin) — avoid
  • strong water tablets (furosemide, ethacrynic acid) — avoid
  • muscle relaxants used in anaesthesia (e.g. succinylcholine)

Pregnancy: may harm an unborn baby — use only if clearly needed

Reference information, not medical advice — always follow your doctor or pharmacist. Source: DailyMed, dailymed.nlm.nih.gov, amikacin sulfate injection label, setid c0f57839-1c9b-49e5-8c7a-708e2d16495d (accessed 2026-08-16)

Approved brands & formulations5

Brand nameDosage formStrengthImporterCategory
AmikacinParenteral ( Injection )500 mg/2ml (250mg/ml)MFDA designated importers with Pre Authorization approval before importhospital
AmikacinParenteral ( Injection )100 mg/mlMFDA designated importers with Pre Authorization approval before importPOM
Amikacin SulphateParenteral ( Injection )1 gmMFDA designated importers with Pre Authorization approval before importhospital
MIKACIN INJParenteral ( Injection- Intravenous )500 mg/2 mlADK Pharmaceutical Company Pvt Ltdhospital
MIKACIN ® INJ 100 mgParenteral ( Injection )50 mg/ml (IP) ( 2ml )ADK Pharmaceutical Company Pvt Ltdhospital
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